New gene delivery vehicle shows promise for human brain gene therapy
“In a new study published in Science, the team showed [MORE]
Ring’s ‘new class of viral vector’ is re-dosable in primates, overcoming key challenge of AAVs
“AAVs are the most commonly used [MORE]
Glaucoma
“The major risk factor for glaucoma is elevated intraocular pressure, which is regulated by the balance between the secretion of [MORE]
Engineering a virus trap
From the Technical University of Munich: “DNA molecules can be folded into two- and three-dimensional structures. Binding [MORE]
George Church launches gene therapy startup to design safer viral vectors
A bioengineering team at Harvard “has developed a way to [MORE]
Jude Samulski PhD work in gene therapy improves outcomes for DMD
Duchenne Muscular Dystrophy was one of the early targets for [MORE]
Base editing for restoring hearing in mice
From Harvard researchers: “[We] used base editing methods to treat a mouse model of [MORE]
Adeno-associated virus serotype
Adeno-associated viral vectors are a workhorse for gene transfer protocols. Getting enough AAV for gene therapy however has [MORE]
Telomeres
Whether or not Elizabeth Parrish turns out to be the hero of her own story, only time will tell. She [MORE]
AAV2 Ribbon Diagram
Adeno-associated virus looked like a promising vector for gene therapy in the mid-1990s, but then sank with the [MORE]