Public attitudes, interests, and concernsregarding polygenic embryo screening

“Polygenic embryo screening (PES), also known as preimplantation genetic testing for polygenic outcomes (PGT-P), is an emerging biotechnology currently used in the context of in vitro fertilization (IVF) to screen and rank individual embryos for their future genetic likelihood of developing common, complex health conditions. Until recently, preimplantation genetic testing was limited to monogenic conditions that occur due to single-gene variations (eg, sickle cell disease). However, with the advent of genome-wide association studies, polygenic scores have been developed for predicting physical health conditions (eg, coronary heart disease or type 1 diabetes), psychiatric health conditions (eg, schizophrenia or depression), behavioral traits (eg, educational attainment or extraversion), and physical traits (eg, height or skin color).”       MORE

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