Kidneys Pump as well as Filter
July 26, 2022 | Terry Sharrer
“Here, using a microfluidic platform to recapitulate fluid transport activity of kidney cells, we [researchers at [Johns Hopkins University] report that renal epithelial cells can actively generate hydraulic pressure gradients across the epithelium. The fluidic flux declines with increasing hydraulic pressure until a stall pressure, in a manner similar to mechanical fluid pumps. For normal human kidney cells, the fluidic flux is from apical to basal, and the pressure is higher on the basal side.” MORE
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