Targeting Stem Cells in Treating Leukemia
January 18, 2022 | Terry Sharrer

Chemotherapy-free stem cell transplant for Leukemia
“In the new study, the researchers [at Washington University in St. Louis] developed a technique that doesn’t require radiation or chemotherapy. Instead, the stem cells in bone marrow are targeted for destruction more precisely, using molecules called antibody-drug conjugates (ADCs). These bind to specific proteins on the surface of blood stem cells, which the team says keeps them from harming other cells. Once they reach their target, the ADCs release a drug called saporin to kill the stem cells.” MORE
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