Single cell reconstruction of adult human heart

From fourteen healthy adult hearts that were rejected after transplantation, a research team headed by a Howard Hughes Medical institute investigator, has produced a map of heart’s morphology, RNA expression and protein profile.  Among other things: “the new atlas revealed some biological surprises. The team found previously unknown cell diversity in various parts of the heart. They also uncovered differences between the healthy hearts of males and females; females had a greater proportion of heart muscle cells, called cardiomyocytes, than males.”  Click on the Nature link for the published article.   MORE

Image Credit:  Nature.com