Genetic modifiers science chart

“Based in San Francisco, Maze Therapeutics (Maze) is studying modifier genes—genes that affect the phenotype or physical properties of other genes—and attempting to create drugs that replicate them . . .   Maze believes that genetic modifiers could afford a “natural form of protection” against disease. In one approach, Maze uses CRISPR Cas9 gene editing to create genome wide gene knockout screens” as means for reducing the ravages of amyotrophic lateral sclerosis (ALS).    MORE

Image Credit:  Maze Therapeutics