First Count of Growth Factors in a Single Cell
April 30, 2019 | Terry Sharrer
Bioengineers at the University of Illinois, Urbana-Champaign “report digital counting of growth factors in single cells using fluorescent quantum dots and calibrated three-dimensional deconvolution microscopy (QDC-3DM) to reveal physiologically relevant cell stimulation distributions. We calibrate the fluorescence intensities of individual compact quantum dots labeled with epidermal growth factor (EGF) and demonstrate the necessity of near-infrared emission to overcome intrinsic cellular autofluoresence at the single-molecule level.” MORE
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