Implantable Device for Breast Cancer Immunotherapy
“To fulfill the unmet clinical need for sustained local drug delivery and to avoid repeated intratumoral injections, we [a collaboration between cancer scientists in Houston, TX and Milan, Italy] developed a nanofluidic-based device for intratumoral drug delivery called the nanofluidic drug-eluting seed (NDES). The NDES is inserted intratumorally using a minimally invasive trocar method similar to brachytherapy seed insertion and offers a clinical advantage of drug elution. Drug diffusion from the NDES is regulated by physical and electrostatic nanoconfinement, thereby resulting in constant and sustained immunotherapeutic delivery without the need for injections or clinician intervention.” MORE
Nanodevice for drug delivery directly to tumor Jan 1 19. Image Credit: Houston Methodist Research Institute News