Quick and Cheap, Brain-in-a-Dish
November 6, 2018 | Terry Sharrer
In addition to animal models and single cells, drug researchers have organoids derived from reprogrammed stem cells for testing. This piece tells of such work at the University of California’s Stem Cell Program in San Diego where researchers have developed cerebral organoids which function at the gene expression level. “To do so, they compressed and optimized several steps of the process so that somatic cells are reprogrammed, expanded and stimulated to form cortical cells almost simultaneously. The result is a cortical organoid that fully develops from somatic cells with only minor manipulation.” MORE
Image Credit: Alysson Muotri, UC San Diego Health