MUSE Microscope Uses UV Light for Diagnosis
“MUSE” means Microscopy with Ultraviolet Surface Excitation,” and it is a new way of doing histology without the traditional formalin fixation, paraffin embedding and thin sectioning. University of California at Davis scientists developed this method which “uses ultraviolet light at wavelengths below the 300 nanometer range to penetrate the surface of tissue samples by only a few microns (about the same thickness of tissue slices on traditional microscope slides.). . . . Samples that have been stained with eosin or other standard dyes to highlight important features such as nuclei, cytoplasm and extracellular components produce signals from the UV excitation that are bright enough to be detected by conventional color cameras using sub-second exposure times. The process allows for rapid imaging of large areas and immediate interpretation.” By rapid, they mean in minutes. MORE
Image Credit: UC Davis Health