RNA Sequencing with a Microfluidics Device
October 17, 2017 | Terry Sharrer
In order to map a brain, investigators have to show different cells types, and differences in each cell type during developmental stages. Single cell RNA sequencing has made this possible, but with billions of cells in a single brain, it is virtually impossible to map by one cell at a time. Broad Institute and Harvard scientists have improved this picture using a microfluidics device with a massively parallel RNA sequencing technique called “DroNc-Seq” that can “a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtypes.” MORE
Image Credit: Susannah M. Hamilton and Tom Ulrich, Broad Communications
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