Tissue Regeneration through Metabolic Control
January 7, 2014 | Terry Sharrer
Since James Till and Ernest McColloch first proved the existence of stem cells in 1961, researchers came to realize that expressions of RNA binding proteins probably explain how stem cells carry out changing tissue growth over an organism’s life span. Now, advancing that knowledge two lab groups at the University of Texas Southwestern Medical Center (Dallas) have identified two of what they consider to be a network of RNA binding proteins that are present in fetal development but turned off in later life. One of those, Lin 28a, involves metabolic activation and suggests that drugs which modulate metabolism could improve tissue repair. MORE