Molecular Sensor for MS
January 28, 2014 | Terry Sharrer

Advamced Imaging of Thrombin
Neuroscientists at the University of California, San Francisco have shown how disruption of the blood brain barrier allows fibrinogen to seep into the brain where another protein, thrombin, converts it to fibrin. In response, the immune system attacks the fibrin and by so doing begins the cascade of deterioration leading to multiple sclerosis. Knowing this, the researchers have identified thrombin as a target for a fluorescently labeled probe, allowing early diagnose of the disease. MORE
Image Credit: Dimitrios Davalos/Kim Baeten/Katerina Akassoglou, Gladstone Institutes, UCSF Partner