iRNA

In 1998, Craig Mello and Andrew Fire published their research on small snippets of RNA which they believed had therapeutic potential for silencing gene expression.  Seven years later, they shared the Nobel Prize for that work, and now Mello and colleagues are working toward a human clinical trial, where the therapy would involve injecting a modified interfering RNA (iRNA) beneath the dermis of a surgical site to inhibit the gene expression of a tissue growth factor, thus preventing or minimizing scaring.       MORE

Image Credit:  RX1Pharmaceuticals and Technology Review