A New Twist on the Biochemistry of Alzheimer’s Disease
July 5, 2011 | Terry Sharrer
For many years, neuroscientists have focused on the role amyloid beta plays in the plaques and tangles of neurons of AD patients. Fine details about how that happens have been hard won, but a group at UC-Santa Barbara now proposes that the tau protein, known to be implicated in abnormal neuron phosphorylation actually destroys the cytoskeletons of those cells. Better diagnosis and treatments, of course, depend on understanding this molecular pathology. MORE